The Chamber has created an Advisory Board which currently includes the following business and political leaders in both SA and the UK:
- HE Kingsley Mamabolo – SA High Commissioner to the UK
- HE Antony Phillipson – UK High Commissioner to SA
- John Battersby, Journalist and retired SA Chamber Director
- Prof. Nicholas Binedell – Gordon Institute of Business Science (GIBS)
- Paul Bondi – Co Head South Africa, Rothschild & Sons
- Mohamed Cassimjee
- Tanya Cohen
- Cheryl Buss – ABSA
- Kuseni Dlamini – Chairman of Massmart and Aspen Pharmaceuticals
- Jason Goodall – CEO of Dimension Data UK
- Adam Habib – Director SOAS University
- Dean MacPherson – Democratic Alliance KwaZulu-Natal Chairperson
- Jacko Maree – Standard Bank – Deputy Chairman, Investment Envoy to SA President
- Mike Miller – SAPRO
- Richard Morgan – Anglo – Head of Government Relations
- Amol Prahbu – Barclays international – Country CEO South Africa & Market Head Africa
- Deva Ponnoosami – Businessman and Founder Member
- Andrew Skipper MBE – Founder and CEO – Polymetis Professional Solutions
- Moses Tembe – Bellamont Investements